The Intestine, or simply called “gut” plays a vital role in our overall health and well-being. It can help control everything from our weight to our mood to brain health, inflammation and immune function. Moreover, 90% of serotonin, the happy hormone, is also produced in the gut.
The main function of the intestinal barrier is to regulate the absorption of the nutrients including of electrolytes and water from the lumen into the circulation, preventing the growth of harmful microflora species, synthesizing nutrients (such as biotin and vitamin K), neutralizing toxins, stimulating the immune system. Interestingly, those functions would not happen without assistance from our gut microbiome. There are up to 1,000 species of bacteria in the human gut microbiome, and each of them plays a different role in our body. Most of them are extremely important for our
health, while some other bacteria, viruses and fungi may cause disease.
There are some researches showing that the brain-gut-microbiome axis is associated with a nervous, endocrine and immune system. The interactive relationship between the brain and the gut includes neurology, metabolism, hormones, immunity, and other aspects. Changes in any component may lead to a functional change in the two interactive systems. The normal ecological balance of gut microorganisms plays an important role in the maintenance of this relationship. Dysbiosis as the changes in gut microbiota composition correlation with diseases such as irritable bowel syndrome (IBS) and other functional gastrointestinal disorders, autism, Parkinson’s disease, multiple sclerosis, obesity, depression, etc. Gut microbiota dysbiosis have been associated with the food allergy and is induced by cesarean delivery, drug (antibiotic), a low-fiber, high-fat diet.
Nowadays, we can test our gut health. GI Effects Stool Profiles is a comprehensive evaluation of GI function. Evaluating the microbial community of the GI tract microbiota, assessment of bacteria, yeast, and parasites. Biomarkers that indicate inflammatory changes in the GI tract, digestion and absorption, microbiome imbalances, markers of undigested protein reaching the colon. From the result leads us to therapeutic interventions, such as dietary macronutrient content, fiber supplementation, prebiotics, probiotics, symbiotics, lifestyle modification.